General Information

  • ID:  hor001998
  • Uniprot ID:  NA
  • Protein name:  GnRH II
  • Gene name:  NA
  • Organism:  Marmoset Monkeys
  • Family:  GnRH family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EHWSGLRPG
  • Length:  9
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T10 Glycine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Stimulate inositol phosphate production via the marmoset type II receptor, increased the frequency of total proceptive behavior
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001998_AF2.pdbhor001998_ESM.pdb

Physical Information

Mass: 118100 Formula: C46H67N15O13
Absent amino acids: ACDFIKMNQTVY Common amino acids: G
pI: 7.55 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 2
Hydrophobicity: -127.78 Boman Index: -2066
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 43.33
Instability Index: 4011.11 Extinction Coefficient cystines: 5500
Absorbance 280nm: 687.5

Literature

  • PubMed ID:  16179411
  • Title:  Gonadotropin-releasing Hormone II Stimulates Female Sexual Behavior in Marmoset Monkeys